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One Stop Pharmacokinetic Program:
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- Many novel features
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Applicable to most drugs
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Easy
to use
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Detailed graphical output
New revised version:
PKQuest_Java3.2 - August, 2011:
Added features: 1) Deconvolution; 2) Non-compartmental
Pharmcokinetics; 3) Direct fit to individual tissues.
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Free Java Based Interactive Version.
Complete PBPK software package.
Features:
Intuitive and versatile
interactive interface.
Uses pre-programmed optimized human
parameter set
Allows time dependent PBPK parameters
Non-linear parameter optimization
Unique solution for oral "first pass
metabolism" of non-linear solutes
Volatile solutes and alveolar
perfusion/ventilation heterogeneity
Input and output of Excel spreadsheet
data
Antecubital vein sampling
... and much more
Download
PKQuest_Java
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Novel features and
applications are illustrated in a series of
publications evaluating deconvolution techniques and describing the human pharmacokinetics of:
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- D2O
- Propranolol
- Ethanol
- Inulin
- Dicloxacillin
- Ceftriaxone
- Toluene
- Nitrous Oxide
- Enflurane
- Halothane
- Methoxyflurane
- Toluene
- Propofol
- And Many More - See Publications
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